This paper discusses commercially available materials, current technology and the practice of manufacturing medical devices with lubricious coatings.
The hydrogel discussed in this paper has a unique property in that it crosslinks at room temperature. The hydrogel solution can be applied in acidic or alkaline conditions. Both conditions have their own unique curing profiles and water absorption capabilities.
Ammonia was used to raise the pH of the hydrogel solution and was found to affect layer adhesion, film formation, insoluble matter, water absorption and cure mechanism.