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Video: ExxonMobil exec says innovation is key to growth
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BEACHWOOD, Ohio—An ExxonMobil official painted a bright future for the rubber industry as long as the key players along the entire value chain focus on innovation and the factors driving...
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BEACHWOOD, Ohio—An ExxonMobil official painted a bright future for the rubber industry as long as the key players along the entire value chain focus on innovation and the factors driving rising demand. BEACHWOOD, Ohio—An ExxonMobil official painted a bright future for the rubber industry as long as the key players along the entire value chain focus on innovation and the factors driving rising demand. $BEACHWOOD, Ohio—An ExxonMobil official painted a bright future for the rubber industry as long as the key players along the entire value chain focus on innovation and the factors driving rising demand.
Degenhart: Conti to keep its balance amid high-tech shift
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HANOVER, Germany—Continental A.G. will maintain the position of rubber-based businesses within the group even as it moves to become a leading player in the field of autonomous and connected...
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HANOVER, Germany—Continental will maintain the position of rubber-based businesses within the group even as it moves to become a leading player in the field of autonomous and connected vehicle technologies, according to CEO Elmar Degenhart. HANOVER, Germany—Continental will maintain the position of rubber-based businesses within the group even as it moves to become a leading player in the field of autonomous and connected vehicle technologies, according to CEO Elmar Degenhart. $HANOVER, Germany—Continental will maintain the position of rubber-based businesses within the group even as it moves to become a leading player in the field of autonomous and connected vehicle technologies, according to CEO Elmar Degenhart.
ContiTech expands elevator belt production in Germany
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DANNENBERG, Germany—ContiTech A.G. has expanded its production of elevator belts at its site in Dannenberg to meet growing demand. With a $5.58 million investment, the company has added a...
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DANNENBERG, Germany—ContiTech has expanded its production of elevator belts at its site in Dannenberg to meet growing demand. DANNENBERG, Germany—ContiTech has expanded its production of elevator belts at its site in Dannenberg to meet growing demand. $DANNENBERG, Germany—ContiTech has expanded its production of elevator belts at its site in Dannenberg to meet growing demand.
Bridgestone invests in proactive ride technology
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NASHVILLE, Tenn.—Bridgestone Americas Inc. invested in ClearMotion Inc. a venture-backed technology company developing road-sensing software and hardware that dramatically improves ride...
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NASHVILLE, Tenn.—Bridgestone Americas invested in ClearMotion, a venture-backed technology company developing road-sensing software and hardware that dramatically improves ride performance in cars. NASHVILLE, Tenn.—Bridgestone Americas invested in ClearMotion, a venture-backed technology company developing road-sensing software and hardware that dramatically improves ride performance in cars. $NASHVILLE, Tenn.—Bridgestone Americas invested in ClearMotion, a venture-backed technology company developing road-sensing software and hardware that dramatically improves ride performance in cars.
Sonus follows same path with new name
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WARREN, Mich.—Sonus Engineered Solutions may have a new name, but its mission remains the same. The formerly-named Novo Motor Acoustic Systems Inc., a supplier of automotive parts designed...
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WARREN, Mich.—Sonus Engineered Solutions may have a new name, but its mission remains the same. WARREN, Mich.—Sonus Engineered Solutions may have a new name, but its mission remains the same. $WARREN, Mich.—Sonus Engineered Solutions may have a new name, but its mission remains the same.
Michelin unveils 'Vision' for future
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MONTREAL—A new vision for sustainable mobility in the future, underscored by a new logo, was the big reveal for Michelin at its Movin' On 2017 conference in Montreal June 13-15.Michelin's...
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MONTREAL—A new vision for sustainable mobility in the future, underscored by a new logo, was the big reveal for Michelin at its Movin' On 2017 conference in Montreal June 13-15. MONTREAL—A new vision for sustainable mobility in the future, underscored by a new logo, was the big reveal for Michelin at its Movin' On 2017 conference in Montreal June 13-15. $MONTREAL—A new vision for sustainable mobility in the future, underscored by a new logo, was the big reveal for Michelin at its Movin' On 2017 conference in Montreal June 13-15.
Smithers breaks ground on laboratory expansion
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RAVENNA, Ohio—Independent, third-party laboratory Smithers Rapra broke ground recently on a new expansion at the Smithers Tire and Wheel Test Center in Ravenna. Six of the top global tire...
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RAVENNA, Ohio—Smithers Rapra broke ground on a new expansion at the Smithers Tire and Wheel Test Center in Ravenna. RAVENNA, Ohio—Smithers Rapra broke ground on a new expansion at the Smithers Tire and Wheel Test Center in Ravenna. $RAVENNA, Ohio—Smithers Rapra broke ground on a new expansion at the Smithers Tire and Wheel Test Center in Ravenna.
Wacker opens silicones R&D center in Mich.
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ANN ARBOR, Mich.—Wacker Chemie A.G. has opened its Silicones R&D Center in Ann Arbor that will be used to develop new products for its customers in the Americas. The 10,000-sq.-ft. site ...
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ANN ARBOR, Mich.—Wacker Chemie has opened its Silicones R&D Center in Ann Arbor that will be used to develop new products for its customers in the Americas. ANN ARBOR, Mich.—Wacker Chemie has opened its Silicones R&D Center in Ann Arbor that will be used to develop new products for its customers in the Americas. $ANN ARBOR, Mich.—Wacker Chemie has opened its Silicones R&D Center in Ann Arbor that will be used to develop new products for its customers in the Americas.
Online extra: New fire hose addresses kink-resistant trend
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SAN ANTONIO—One trend on the municipal side of the fire hose market has been toward lower-pressure nozzles to help fight such issues as firefighter fatigue. And while much development work...
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SAN ANTONIO—North American Fire Hose recently introduced a highly kink-resistant fire hose that will work at lower pressure. It's part of an industry trend toward lower-pressures and nozzles which help fight such issues as firefighter fatigue. SAN ANTONIO—North American Fire Hose recently introduced a highly kink-resistant fire hose that will work at lower pressure. It's part of an industry trend toward lower-pressures and nozzles which help fight such issues as firefighter fatigue. $SAN ANTONIO—North American Fire Hose recently introduced a highly kink-resistant fire hose that will work at lower pressure. It's part of an industry trend toward lower-pressures and nozzles which help fight such issues as firefighter fatigue.
New challenges, uncertainty on horizon for automotive industry
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ANN ARBOR, Mich.—The automotive industry has dug itself out of the Great Recession, but there's plenty of uncertainty on the horizon. Light vehicle sales in the U.S. have grown every year...
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ANN ARBOR, Mich.—The automotive industry has dug itself out of the Great Recession, but there's plenty of uncertainty on the horizon. ANN ARBOR, Mich.—The automotive industry has dug itself out of the Great Recession, but there's plenty of uncertainty on the horizon. $ ANN ARBOR, Mich.—The automotive industry has dug itself out of the Great Recession, but there's plenty of uncertainty on the horizon.
Digital Edition
Digital Edition
Published on January 1, 2007

How To Ensure that a Manufactured Latex Product has the Lowest Practicable Allergen Levels

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Date Published January 1, 2007
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This Report has been authored by:Timo Palosuo at Finland National Public Health Institute

Immediate allergic reactions to natural rubber latex (NRL) proteins continue to be an important medical and occupational health problem. Attempts at minimizing protein and allergen concentration in NRL gloves to prevent sensitization and the development clinical allergy to NRL are acknowledged as a goal of mutual interest for rubber manufacturers and regulatory health authorities. Total protein determination has been widely used for the indirect estimation of allergen content in NRL products but consensus exists today that allergen-specific assays that are specific, of high sensitivity and reproducibility and can be properly standardized, would provide much more reliable information. We quantified four NRL allergens (Hev b 1, Hev b 3, Hev b 5 and Hev b 6.02) in 208 glove brands by a capture enzyme immunoassay (FITKit®). The results were compared with those from a skin prick test-validated human IgE-based ELISA-inhibition method that has been considered as the “golden standard” for demonstration of allergenicity of rubber products. A high overall correlation ( r=0.87, 95% CI 0.83 to 0.90) emerged between the sum values of the four allergens(µg/g glove) and IgE-ELISA inhibition. The sum, when set at 0.15 µg/g discriminated “low allergenic” (< 10 AU/ml) from “moderate to high allergenic” (>10 AU/ml) gloves at a sensitivity of 0.93 (95% CI 0.85 to 0.98) and specificity of 0.90 (95% CI 0.83 to 0.94). In conclusion, the allergenic potential of medical gloves could be assessed with remarkably high specificity and sensitivity. For the four allergen sum test we set up a cut-off level (0.15 µg/g) below which virtually all gloves can be considered as low allergenic. Although it is still not possible to make claims of safety, the specific allergen tests will be a very useful practical guide to personnel responsible for glove purchasing in hospitals and health care centers and also to conventional glove users to support their glove selection policies. 
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