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Researchers bring 'Thubber' to life
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PITTSBURGH—"Flubber" was just a joke from the Walt Disney Studios. But "thubber," a thermally conductive rubber material for making soft, stretchable machines and electronics, is now a...
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PITTSBURGH—Researchers at Carnegie Mellon University have developed an electrically insulating composite that offers a combination of metal-like thermal conductivity and elasticity capable of stretching more than six times its initial length. PITTSBURGH—Researchers at Carnegie Mellon University have developed an electrically insulating composite that offers a combination of metal-like thermal conductivity and elasticity capable of stretching more than six times its initial length. $PITTSBURGH—Researchers at Carnegie Mellon University have developed an electrically insulating composite that offers a combination of metal-like thermal conductivity and elasticity capable of stretching more than six times its initial length.
Changed vote makes difference in ITC decision
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WASHINGTON—The shift of one vote caused the International Trade Commission to make a final determination that the U.S. truck and bus tire manufacturing industry is not being materially...
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WASHINGTON—The shift of one vote caused the International Trade Commission to make a final determination that the U.S. truck and bus tire manufacturing industry is not being materially injured because of imports from China. WASHINGTON—The shift of one vote caused the International Trade Commission to make a final determination that the U.S. truck and bus tire manufacturing industry is not being materially injured because of imports from China. $WASHINGTON—The shift of one vote caused the International Trade Commission to make a final determination that the U.S. truck and bus tire manufacturing industry is not being materially injured because of imports from China.
Goodyear, Cooper Tire employees honored with STEP Ahead awards
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AKRON—The Manufacturing Institute will honor five women who work for Goodyear and Cooper Tire & Rubber Co. at its upcoming Women in Manufacturing STEP (Science, Technology, Engineering...
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AKRON—The Manufacturing Institute will honor five women who work for Goodyear and Cooper at its upcoming Women in Manufacturing STEP (Science, Technology, Engineering and Production) Ahead Awards. AKRON—The Manufacturing Institute will honor five women who work for Goodyear and Cooper at its upcoming Women in Manufacturing STEP (Science, Technology, Engineering and Production) Ahead Awards. $AKRON—The Manufacturing Institute will honor five women who work for Goodyear and Cooper at its upcoming Women in Manufacturing STEP (Science, Technology, Engineering and Production) Ahead Awards.
James Walker to unveil new elastomer family
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CHESHIRE, England—A sealing products manufacturer from the United Kingdom is ready to release a new family of elastomers it will use in its goods to meet the ever-increasing demands of the...
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CHESHIRE, England—A sealing products manufacturer from the United Kingdom is ready to release a new family of elastomers it will use in its goods to meet the ever-increasing demands of the oil and gas industry. CHESHIRE, England—A sealing products manufacturer from the United Kingdom is ready to release a new family of elastomers it will use in its goods to meet the ever-increasing demands of the oil and gas industry. $CHESHIRE, England—A sealing products manufacturer from the United Kingdom is ready to release a new family of elastomers it will use in its goods to meet the ever-increasing demands of the oil and gas industry.
Oil and gas market looking up, but profits hard to come by
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WASHINGTON—This year will be better than 2016 for the oil and gas industry and the rubber and polymer product manufacturers that supply them, according to industry officials and experts....
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WASHINGTON—This year will be better than 2016 for the oil and gas industry and the rubber and polymer product manufacturers that supply them, according to industry officials and experts. WASHINGTON—This year will be better than 2016 for the oil and gas industry and the rubber and polymer product manufacturers that supply them, according to industry officials and experts. $WASHINGTON—This year will be better than 2016 for the oil and gas industry and the rubber and polymer product manufacturers that supply them, according to industry officials and experts.
China slides to No. 2 tire trading partner
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AKRON—Canada replaced China last year as the No. 1 trading partner of the U.S. in tires. The value of China's imports to the U.S.—impacted primarily by the cut in consumer tire...
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AKRON—Canada replaced China last year as the No. 1 trading partner of the U.S. in tires. AKRON—Canada replaced China last year as the No. 1 trading partner of the U.S. in tires. $AKRON—Canada replaced China last year as the No. 1 trading partner of the U.S. in tires.
ITC antidumping decision brings mixed reactions
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As with any decision regarding imported tires and tariffs and duties, there are winners and losers.That certainly is the case following the surprising Feb. 22 decision by the U.S. International...
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As with any decision regarding imported tires and tariffs and duties, there are winners and losers. As with any decision regarding imported tires and tariffs and duties, there are winners and losers. $As with any decision regarding imported tires and tariffs and duties, there are winners and losers.
Henkel, Benteler making composite leaf springs for Volvo
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DUESSELDORF, Germany—Laundry and personal care products-to-reactive polyurethane systems company, Henkel A.G. and automotive composites firm Benteler S.G.L. are supplying polyurethane...
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DUESSELDORF, Germany—Henkel and Benteler are supplying polyurethane composite leaf springs to the Volvo S90 and V90 following their introduction on the XC90 crossover SUV. DUESSELDORF, Germany—Henkel and Benteler are supplying polyurethane composite leaf springs to the Volvo S90 and V90 following their introduction on the XC90 crossover SUV. $DUESSELDORF, Germany—Henkel and Benteler are supplying polyurethane composite leaf springs to the Volvo S90 and V90 following their introduction on the XC90 crossover SUV.
Lubrizol invests to grow medical unit
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ANAHEIM, Calif.—Lubrizol Corp.'s LifeSciences unit has added thermoplastic polyurethane compounding abilities through a partnership with a medical compounder. Compounding Solutions, which...
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ANAHEIM, Calif.—Lubrizol's LifeSciences unit has added thermoplastic polyurethane compounding abilities through a partnership with a medical compounder. ANAHEIM, Calif.—Lubrizol's LifeSciences unit has added thermoplastic polyurethane compounding abilities through a partnership with a medical compounder. $ANAHEIM, Calif.—Lubrizol's LifeSciences unit has added thermoplastic polyurethane compounding abilities through a partnership with a medical compounder.
Doublestar inks Kumho deal, but Park counter-offer looms
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SEOUL, South Korea—China's Qingdao Doublestar Co. said it has signed an agreement with Kumho Tire creditors to buy a 42 percent stake in the South Korean tire maker in a deal that could...
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SEOUL, South Korea—Doublestar said it has signed an agreement with Kumho Tire creditors to buy a 42 percent stake in the South Korean tire maker in a deal that could enable Doublestar to further expand in China. SEOUL, South Korea—Doublestar said it has signed an agreement with Kumho Tire creditors to buy a 42 percent stake in the South Korean tire maker in a deal that could enable Doublestar to further expand in China. $SEOUL, South Korea—Doublestar said it has signed an agreement with Kumho Tire creditors to buy a 42 percent stake in the South Korean tire maker in a deal that could enable Doublestar to further expand in China.
Digital Edition
Digital Edition
Published on January 1, 2007

How To Ensure that a Manufactured Latex Product has the Lowest Practicable Allergen Levels

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Date Published January 1, 2007
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This Report has been authored by:Timo Palosuo at Finland National Public Health Institute

Immediate allergic reactions to natural rubber latex (NRL) proteins continue to be an important medical and occupational health problem. Attempts at minimizing protein and allergen concentration in NRL gloves to prevent sensitization and the development clinical allergy to NRL are acknowledged as a goal of mutual interest for rubber manufacturers and regulatory health authorities. Total protein determination has been widely used for the indirect estimation of allergen content in NRL products but consensus exists today that allergen-specific assays that are specific, of high sensitivity and reproducibility and can be properly standardized, would provide much more reliable information. We quantified four NRL allergens (Hev b 1, Hev b 3, Hev b 5 and Hev b 6.02) in 208 glove brands by a capture enzyme immunoassay (FITKit®). The results were compared with those from a skin prick test-validated human IgE-based ELISA-inhibition method that has been considered as the “golden standard” for demonstration of allergenicity of rubber products. A high overall correlation ( r=0.87, 95% CI 0.83 to 0.90) emerged between the sum values of the four allergens(µg/g glove) and IgE-ELISA inhibition. The sum, when set at 0.15 µg/g discriminated “low allergenic” (< 10 AU/ml) from “moderate to high allergenic” (>10 AU/ml) gloves at a sensitivity of 0.93 (95% CI 0.85 to 0.98) and specificity of 0.90 (95% CI 0.83 to 0.94). In conclusion, the allergenic potential of medical gloves could be assessed with remarkably high specificity and sensitivity. For the four allergen sum test we set up a cut-off level (0.15 µg/g) below which virtually all gloves can be considered as low allergenic. Although it is still not possible to make claims of safety, the specific allergen tests will be a very useful practical guide to personnel responsible for glove purchasing in hospitals and health care centers and also to conventional glove users to support their glove selection policies. 
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