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Polyurethane-filled holes improve Wilson's swing
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CHICAGO—Polyurethane is at the heart of the latest generation of Wilson's Distance D300 irons.The new golf clubs incorporate Power Holes, which are through-holes that surround the club's...
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CHICAGO—Polyurethane is at the heart of the latest generation of Wilson's Distance D300 irons. CHICAGO—Polyurethane is at the heart of the latest generation of Wilson's Distance D300 irons. $CHICAGO—Polyurethane is at the heart of the latest generation of Wilson's Distance D300 irons.
Editorial: Two deals show medical to remain a hot business area
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As the rubber industry entered into the new year, it’s clear that the medical industry will remain one of great activity. That was exemplified by two acquisitions closed late in 2016 where...
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As the rubber industry entered into the new year, it's clear that the medical industry will remain one of great activity. As the rubber industry entered into the new year, it's clear that the medical industry will remain one of great activity. $As the rubber industry entered into the new year, it's clear that the medical industry will remain one of great activity.
Withdrawal from NAFTA would cost U.S. jobs, study finds
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DETROIT— President-elect Donald Trump's vows to renegotiate the North American Free Trade Agreement (NAFTA) and pursue more protectionist trade policies likely would have a negative effect...
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DETROIT— President-elect Donald Trump's vows to renegotiate the North American Free Trade Agreement and pursue more protectionist trade policies likely would have a negative effect on the U.S. auto industry, a new study reveals. DETROIT— President-elect Donald Trump's vows to renegotiate the North American Free Trade Agreement and pursue more protectionist trade policies likely would have a negative effect on the U.S. auto industry, a new study reveals. $DETROIT— President-elect Donald Trump's vows to renegotiate the North American Free Trade Agreement and pursue more protectionist trade policies likely would have a negative effect on the U.S. auto industry, a new study reveals.
Semperit, Sri Trang demerge Thai gloves JV
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VIENNA—Austrian rubber company Semperit A.G. and its Thai partner Sri Trang Angro-Industry P.L.C. have agreed to demerge their Siam Sempermed rubber gloves joint venture, following a series...
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VIENNA—Austrian rubber company Semperit and its Thai partner Sri Trang have agreed to demerge their Siam Sempermed rubber gloves joint venture, following a series of legal disputes between the partners. VIENNA—Austrian rubber company Semperit and its Thai partner Sri Trang have agreed to demerge their Siam Sempermed rubber gloves joint venture, following a series of legal disputes between the partners. $VIENNA—Austrian rubber company Semperit and its Thai partner Sri Trang have agreed to demerge their Siam Sempermed rubber gloves joint venture, following a series of legal disputes between the partners.
Nexen, Toyota Tsusho establish sales JV
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TOKYO—Nexen Tire Corp. has established a sales subsidiary in Japan to handle its growing replacement tire business there, and to reinforce its OE supply relationships with Japanese...
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TOKYO—Nexen has established a sales subsidiary in Japan to handle its growing replacement tire business there, and to reinforce its OE supply relationships with Japanese automobile manufacturers. TOKYO—Nexen has established a sales subsidiary in Japan to handle its growing replacement tire business there, and to reinforce its OE supply relationships with Japanese automobile manufacturers. $TOKYO—Nexen has established a sales subsidiary in Japan to handle its growing replacement tire business there, and to reinforce its OE supply relationships with Japanese automobile manufacturers.
Kanodia sentenced for Cooper-Apollo insider trading scheme
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BOSTON—A Brookline, Mass.-based entrepreneur and private equity investor has been sentenced to 20 months in prison for initiating an insider trading scheme in connection with the failed...
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BOSTON—A Brookline, Mass.-based entrepreneur and private equity investor has been sentenced to 20 months in prison for initiating an insider trading scheme in connection with the failed acquisition of Cooper Tire by Apollo Tyres. BOSTON—A Brookline, Mass.-based entrepreneur and private equity investor has been sentenced to 20 months in prison for initiating an insider trading scheme in connection with the failed acquisition of Cooper Tire by Apollo Tyres. $BOSTON—A Brookline, Mass.-based entrepreneur and private equity investor has been sentenced to 20 months in prison for initiating an insider trading scheme in connection with the failed acquisition of Cooper Tire by Apollo Tyres.
Wacker to add fumed silica plant at Tennessee campus
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CHARLESTON, Tenn.—Wacker Chemie A.G. intends to invest $150 million to establish a new pyrogenic silica facility on the same site as its existing plant in Charleston. Construction is...
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CHARLESTON, Tenn.—Wacker intends to invest $150 million to establish a new pyrogenic silica facility on the same site as its existing plant in Charleston. CHARLESTON, Tenn.—Wacker intends to invest $150 million to establish a new pyrogenic silica facility on the same site as its existing plant in Charleston. $CHARLESTON, Tenn.—Wacker intends to invest $150 million to establish a new pyrogenic silica facility on the same site as its existing plant in Charleston.
Thailand building auto test center to support tire, NR sectors
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BANGKOK—The Thailand Board of Investment plans to invest $100 million to build an automotive testing center that the government views as a "top priority" for supporting the nation's growing ...
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BANGKOK—The Thailand Board of Investment plans to invest $100 million to build an automotive testing center that the government views as a "top priority" for supporting the nation's growing tire and natural rubber industries. BANGKOK—The Thailand Board of Investment plans to invest $100 million to build an automotive testing center that the government views as a "top priority" for supporting the nation's growing tire and natural rubber industries. $BANGKOK—The Thailand Board of Investment plans to invest $100 million to build an automotive testing center that the government views as a "top priority" for supporting the nation's growing tire and natural rubber industries.
Nexteer, Continental to form joint venture
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DETROIT—Nexteer Automotive Corp. and Continental Automotive Systems Inc. will form a joint venture to supply safety systems for autonomous cars.In an announcement Tuesday at the North...
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DETROIT—Nexteer and Continental Automotive Systems will form a joint venture to supply safety systems for autonomous cars. DETROIT—Nexteer and Continental Automotive Systems will form a joint venture to supply safety systems for autonomous cars. $DETROIT—Nexteer and Continental Automotive Systems will form a joint venture to supply safety systems for autonomous cars.
Toyo plans North American expansion
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WHITE, Ga.—Toyo Tire & Rubber Co. Ltd. plans to expand its North American research and development center, setting up a dedicated business development unit for the market. The firm, in...
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WHITE, Ga.—Toyo Tire plans to expand its North American research and development center, setting up a dedicated business development unit for the market. WHITE, Ga.—Toyo Tire plans to expand its North American research and development center, setting up a dedicated business development unit for the market. $WHITE, Ga.—Toyo Tire plans to expand its North American research and development center, setting up a dedicated business development unit for the market.
Digital Edition
Digital Edition
Published on January 1, 2007

How To Ensure that a Manufactured Latex Product has the Lowest Practicable Allergen Levels

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Date Published January 1, 2007
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This Report has been authored by:Timo Palosuo at Finland National Public Health Institute

Immediate allergic reactions to natural rubber latex (NRL) proteins continue to be an important medical and occupational health problem. Attempts at minimizing protein and allergen concentration in NRL gloves to prevent sensitization and the development clinical allergy to NRL are acknowledged as a goal of mutual interest for rubber manufacturers and regulatory health authorities. Total protein determination has been widely used for the indirect estimation of allergen content in NRL products but consensus exists today that allergen-specific assays that are specific, of high sensitivity and reproducibility and can be properly standardized, would provide much more reliable information. We quantified four NRL allergens (Hev b 1, Hev b 3, Hev b 5 and Hev b 6.02) in 208 glove brands by a capture enzyme immunoassay (FITKit®). The results were compared with those from a skin prick test-validated human IgE-based ELISA-inhibition method that has been considered as the “golden standard” for demonstration of allergenicity of rubber products. A high overall correlation ( r=0.87, 95% CI 0.83 to 0.90) emerged between the sum values of the four allergens(µg/g glove) and IgE-ELISA inhibition. The sum, when set at 0.15 µg/g discriminated “low allergenic” (< 10 AU/ml) from “moderate to high allergenic” (>10 AU/ml) gloves at a sensitivity of 0.93 (95% CI 0.85 to 0.98) and specificity of 0.90 (95% CI 0.83 to 0.94). In conclusion, the allergenic potential of medical gloves could be assessed with remarkably high specificity and sensitivity. For the four allergen sum test we set up a cut-off level (0.15 µg/g) below which virtually all gloves can be considered as low allergenic. Although it is still not possible to make claims of safety, the specific allergen tests will be a very useful practical guide to personnel responsible for glove purchasing in hospitals and health care centers and also to conventional glove users to support their glove selection policies.